Neurology
·Neurology
Movement Disorders — Pattern Recognition
⭐ PREMIUM
PARKINSON DISEASE — TRAP
• Tremor (resting, pill-rolling, 4–6 Hz)
• Rigidity (cogwheel)
• Akinesia / Bradykinesia
• Postural instability
Plus mask facies, festinating gait, micrographia, REM sleep behaviour disorder
Pathology: loss of dopaminergic neurons in substantia nigra, Lewy bodies (α-synuclein)
Treatment: levodopa-carbidopa, dopamine agonists (ropinirole, pramipexole), MAO-B (selegiline…
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